Aseptic fill-finish.
Built for optionality.
Spanance is building a next-generation aseptic fill-finish CDMO in Portugal, designed to support sterile injectable programs from clinical batches through commercial scale.
Our modular approach combines flexible manufacturing architecture with isolator-based technology, enabling us to adapt to different program sizes, product formats and partner requirements.
ADVANCING SCIENCE,
ENHANCING LIFE
Location
(Mação, Santarém)
cleanroom
footprint
Aseptic fill-finish
Multiple
rooms
with independent
HVAC
Multi-format RTU
Vials • PFS • Cartridges
Location
(Mação, Santarém)
cleanroom
footprint
Aseptic
fill-finish
rooms
with independent
HVAC
Multi-format
RTU
Vials • PFS • Cartridges
ABOUT
A CDMO that keeps
options open
ABOUT
A CDMO that keeps
options open
Spanance is focused on downstream pharmaceutical manufacturing, with aseptic fill-finish at the core of our platform. Our modular approach is designed to accommodate different product formats, batch sizes and stages of development while supporting efficient scale-up and technology transfer.
Versatile facilities
Our 3,000 m² GMP-designed facility in Mação is being developed around modular, independently controlled production areas and an isolator-based aseptic fill-finish platform.
The facility is designed to support compliance with EU GMP Annex 1, combining controlled manufacturing environments with the flexibility to accommodate different batch sizes, formats and future capacity requirements.
Capabilities
Capabilities in focus
From clinical batches to commercial scale
- Filling of vials, pre-filled syringes and cartridges
- Isolator-based aseptic processing
- Flexible batch sizes and scalable manufacturing programs
Building the path to manufacturing
- Technology transfer and process scale-up
- Validation and manufacturing readiness
- Coordination of analytical and regulatory requirements
Capacity that adapts to the program
- Modular rooms and manufacturing flows
- Flexibility across products, formats and batch sizes
- Expansion pathways aligned with partner and market needs
Open for partnerships
We are engaging with pharmaceutical and biotechnology companies looking for flexible aseptic fill-finish capacity in Europe. If you’re seeking a nimble manufacturing partner – or a site to anchor a program – let’s talk.
